Reactions Between Secondary Amines and Organo-Halogenating Agents

摘要

Kinetics of chlorine acceptance by succinimide suggests that the negative ionic form of the imide is responsible for the main course of the reaction. Additional data were obtained on the rate of reversible halogen transfer from N-chlorosuccinimide (NCSI) to various secondary amines. Preliminary results on the reactions of quinuclidine with halogenating agents indicate the great stability of the resulting chloroammonium form. The rate of formation of this species from hypochlorous acid and the base was determined. Although the mechanism of breakdown of NCSI in solution has not as yet been solved, several additional bits of information were obtained. (Author)