Contract No.DA-49-193-MD-2146 P. R. No.241 Interim Report for the Period DECEMBER 1963 TO February 1964

摘要

In connection with work previously reported the intensity of the radiation produced by two different quartz lamps was measured actinometrically under the same conditions employed for the irradiation of albumin solutions. The intensities of radiation of the two lamps are 6.0 x 104 ergs ml-l sec-l and 5.3 x 104 ergs ml-1 sec-1 respectively.nThe studies of the catalytic protein waves were extended to protein solutions containing guanidine hydrochloride. The waves of guanidine de-natured albumin are much higher while those of irradiation denatured albumin are lower than that of a native albumin solution. The explanation is that the albumin molecule may have different structures if subjected to different methods of denaturation. This is substantiated by viscosity measurements of untreated and guanidine denatured albumin before and after UV irradiation.