The Chemical Distribution of 11C after Proton Irradiation of Inulin in Dilute Water Solution

摘要

Inulin in both aerated and de-aerated water solutions, in the concentration range 0.00001 to 0.01 g/ml, was irradiated with 60 MeV protons. The reaction products were separated on Sephadex into a low and a high molecular fraction. The distribution of the induced carbon-11 activity between the two fractions was studied and it was found that up to 50% of the activity was bound to molecules of high molecular weight. The scavenging efficiency was found to be dependent on the dose rate and seen to be decreasing with reduced beam current. The possibility of labelling organic compounds by direct proton irradiation in water solutions is discussed. (Author)