HOST PRECIPITIN ANTIBODY PRODUCTION IN RELATION TO DIFFERENTIATION AND GROWTH OF PARASITIC ROUNDWORMS

摘要

Preliminary work in this laboratory has shown that the antigenic com¬ponents of T. spiralis larvae can be separated electrophoretically and antibodies demonstrated by immunodiffusion. Also, during early part of this work it was determined that there was the appearance of new precipitating antibodies during the course of infection.nAs stated previously, the main function of this work was to relate the development and changes in precipitating antibodies to the morphological changes during growth of T. spiralis larvae by immunoelectrophoresis and histological techniques. During the course of this study it was also found necessary to attempt cross reaction studies with other parasitic worms and attempt to isolate the different antigenic components.