SEROLOGICAL INVESTIGATIONS ON THE PLAGUE. REPORT 14. TESTING OF CERTAIN SEROLOGICAL REACTIONS IN EPIZOOTOLOGIC EXAMINATION IN NATURAL PLAGUE FOCI,

摘要

Conclusions: The hemagglutination-inhibition and antibody-neutralization reactions with formalinized erythrocytes can be used under two conditions for the purpose of epizootological examination for plague of wild rodents. It was shown that wild rodents which contain antibodies to plague bacillus in their blood are found significantly oftener in a natural focus than animals from which the causative agent can be isolated. From results of the hemagglutination-inhibition reaction,the intensity and approximate times of plague epizootics can be estimated (from antibodies in young animals). The antibody-neutralization reaction can advisably be used in investigating perished biopsy animals,decaying material,when isolation of the plague causative microorganism represents great difficulty and is not always possible,and also in other cases when there is a need for rapid diagnosis of plague infection. (Author)