A Study of the Specific Location of Leptospires with Respect to Various Tissue Cells of Infected Animal Hosts

摘要

The objectives of the research were as follows: (1) To determine the specific location of leptospires with respect to various tissue cells of the infected animal host. (2) To study histologic variations at the cellular level as a result of leptospiral activity. (3) To determine final disposition and significance of morphologically intact leptospires within vesicular structures of hepatic and renal cells and (4) To compare the 3341 and MLS strain of Leptospira pomona as to their capability to produce the shedding state in hamsters. (Author)