Purification of Histamine Sensitizing Factor of Bordetella Pertussis

摘要

Attempts were made to separate HSF from Pl as a starting material, since the HSF activity of culture supernate was more than ten times higher than that of the ribosomal fraction. For the solubilization with increasing specific activity successive extraction of Pl with water at pH 6.7 will be necessary using mice, strain ICR, as assay animals. (Author)