Physiologic and Biochemical Observations on the Rhesus Macaca Mulatta Exposed to Oxygen-Rich Atmospheres

摘要

Adolescent male rhesus monkeys (Macaca mulatta), weighing 2.9 to 3.4 kg., were exposed to 100% oxygen atmospheres at 258 and 380 mm. Hg pressures for 30 and 22 days, respectively, and the results obtained were compared to the observations made in a ground-level control study using the same chamber system. Physiologic, hematologic, enzymatic, biochemical, and anatomic measurements were obtained throughout the experiments. Several changes and trends were common to all three experiments; however, some were observed only for the oxygen-exposed animals and were dependent on the concentration of oxygen in the atmosphere. (Author)