CHIMPANZEE PHYSIOLOGICAL TOLERANCE TO BREATHING 100% OXYGEN AT 15PSI,

摘要

In a counterbalanced experiment four restrained,immature chimpanzees were subjected to a 100% oxygen environment at 14.7psia for over 15hours. During this period they were isolated in a chamber and performed various psychomotor tasks. These same animals served as subjects for the same period of time in a 20% oxygen environment. Relative humidity was maintained at 45 - 55%;temperature was maintained at 79 - 81F;environmental CO2was lower than 3.8mm Hg. Heart rate,respiratory rate,and skin and rectal temperatures were monitored during the experiments. Clinical examinations, hematological and serum biochemical determinations,and urinalyses were performed before and following each test. The only significant findings were a relative bradycardia and tachypnea in the hyperoxygenated environment. (Author)