Energy, Nitrogen, and Water Requirements of Normal Adults Residing at 4300 Meters for 28 Days

摘要

Balance studies were conducted on three groups of young, healthy adults between the ages of 18-24 years. After control studies, Group I was taken to 4300 meters gradually, Group II was taken to 4300 meters abruptly, and Group III remained at sea level during the entire study. One-half of each group were physically conditioned. No significant differences were observed in nitrogen, and fluid balances between: (a) the groups that were taken to altitude gradually or abruptly, or (b) between the groups that were physically conditioned, and those who did not exercise. As a result, the respective groups were combined for comparative purposes. Three factors were prominent during the 28 day high altitude exposure to 4300 meters that included: (a) a decrease in food intake which is probably due to anorexia caused by the clinical symptoms; (b) a negative nitrogen balance which may be due to the decreased nutrient intake and the increased requirement for energy; and (c) a negative fluid balance due to involuntary dehydration and other undetermined factors. These factors appeared to be somewhat less in Group I who ascended to altitude gradually, and suggests the beneficial effects of ascending to high altitude gradually. (Author)