Comparison of Strains of Rats Exposed to Oxygen at Various Pressures.

摘要

The response of two strains of rats to 258, 700, and 760 mm Hg atmospheres containing 96-98% oxygen were compared. The Wistar strain was more sensitive to these atmospheres than the SPF Sprague-Dawley strain. Pulmonary lesions seen in Wistar rats exposed to 258 and 700 mm Hg were not characteristic of those reported for acute oxygen toxicity and may represent a pathologic response to a combination of reduced pressure and 96-98% oxygen atmosphere. (Author)