Effect of Physical Factors on Red Cells Subject to Freezing and Thawing

摘要

The storage of ACD blood can be extended to eight weeks if the blood is incubated with adenine-inosine at the end of the storage period, when measure of viability is based on the accepted standard of an average survival of 70% or better of radioactivity of Cr51 tagged erythrocytes 24 hour posttransfusion. Evidence suggests that the absolute increase in ATP following incubation with adenine-inosine may not per se be solely responsible for the increased viability of erythrocytes.