Bile Acids and Lipid Metabolism Ii. Essential Role of Bile Acids in Bile Phospholipid Excretion

摘要

The isolated rat liver perfusion system has been used to study the release of bile phospholipid P32 following the injection of inorganic P32 into the perfusate. It was demonstrated that in the absence of added bile salt very little PLP32 was excreted into bile, but when bile salt was added to the perfusate, the PLP32 excretion increased markedly. It is suggested that bile acids play an essential role in the transport of phospholipid from liver to bile. (Author)