Mibt and Bacteriophage Multiplication

摘要

N-methyl isatin-beta-thiosemicarbazone, a known inhibitor of pox-virus in vitro and in vivo, is without effect upon the virulent bacteriophage T4, T4B, T4Bo1, or the temperate phage lambda grown in E. coli. At concentrations which show striking anti-viral activity against the pox-virus in tissue culture, this compound exhibits no activity in the processes of adsorption, penetration, or replication of the bacteriophage studied. (Author)