Synthesis of Ferrocenecarboxylic Acids and Their Derivatives

摘要

Following a tabulation of known methods for synthesis of ferrocenedicarboxylic acids, the paper reports on methods for which increased yields are claimed. Ferrocenecarboxylic acid was prepared (yield 45.2 percent of theory) by hypochlorite oxidation of acetylferrocene, ferrocene-1,1' -dicarboxylic acid (90-92 percent) by similar oxidation of 1,1' diacetylferrocene, carbamylferrocene (70-72 percent) by direct reaction of ferrocene with carbamyl chloride in the presence of AlCl3, and 1,1' -dicarbamylferrocene (almost 100 percent) by passing ammonia through a benzol solution of the diacid chloride. (Author)