Comparison of Autologous and Non-Autologous Transfusions of Acid-Adenine Blood

摘要

Examination of blood stored in ACD with and without adenine for several time periods was carried out in normal volunteers under ideal conditions using selected in vitro 24-hour posttransfusion survival levels. None of these tests detected any significant difference between autologous and non-autologous transfusions, even when universal donor group O blood was transfused. The changes that did occur were limited to evidence of greater red cell breakdown in units with ACD compared to ACD with adenine. Blood stored in adenine had higher survival values at all storage periods and over 70% 24-hour posttransfusion survival, even after 42 days of storage as compared to blood stored in ACD. Thus, blood stored in adenine appears to be a better preserved product at the routine storage periods, and maintains adequate survival levels, even after 42 days of storage. (Author)