Investigation on Filariasis in Thailand

摘要

A pilot project for the control of Malayan filariasis - mass treatment with diethylcarbamazine at a dose of 5 mgm per kgm body weight once weekly for six weeks was applied to the people of village no. 2 of Kanchanadit District, Surathani Province, South Thailand. The microfilarial positive rate was 21.1 percent and elephantiasis 5.3 percent in the population of about 1000. The causative parasite was nocturnal periodic B. Malayi and there were no animal reservoir hosts. Blood examinations were repeated one month and one, two, three, five and six years after the treatment. Spraying all the houses in the village with DDT, according to the malaria eradication project in Thailand, was also performed once a year. It was found that the incidence of microfilaria-carriers decreased from 21.1 to 0.9 percent, the filariasis infection rate from 26.1 to 6.4 percent, and the mean microfilarial density of all films from 4.8 per 20 cc blood to 0.02. Dissections of the mosquitoes which were performed along with the blood examinations (one month and one, two, three, five and six years after the mass therapy) revealed that only the state II larvae of B. Malayi were found in two M. uniformis caught in the second year after the mass treatment. (2) Malayan filariasis in Chumporn Province, (3) Bancroftian filariasis in Sangkla-Buri District, and (4) skin tests, other portions of the study are reported. (Author)