Pathogenic Properties of Staphylococcus Aureus as Influenced by Culture Conditions

摘要

Broth cultures of Staphylococcus aureus were treated with 100% oxygen or room air and constantly agitated on a mechanical shaker to determine the effect on coagulase, hemolysin, Phosphatase, fibrinolysin, lipase. DNase, and hyaluronidase. Elevated coagulase titers and increased phosphatase activity closely paralleled a simultaneous increase in bacterial cell count. Hemolysin activity of the oxygenated culture decreased. Lipase activity was measurable from the 7th and 14th days for oxygen and air-treated cultures, respectively. Evidence of fibrinolysin or hyaluronidase could not be shown. No apparent increase of DNase was demonstrated. (Author)