A Hamster Model for Streptococcal Impetigo.

摘要

An animal model of impetigo is described in which group A, type 12 beta-hemolytic streptococci were injected intradermally into the back of the Syrian hamster. Seventy-two (96%) of 75 animals so inoculated developed a lesion similar to human impetigo, from which streptococci were recovered for as long as 22 days. The model resembles human impetigo, is readily sampled repeatedly, and remains relatively free of extraneous organisms during the test period. (Author)