Effect of 90-Day Exposure to 1% CO2 on Acid-Base Status of Blood

摘要

Four test subjects were exposed to a 90-day simulated space station environment along with three outside controls. The environmental level of CO2 was comparable (1% CO2) to that found in FBM submarines during extended patrols of 60 days duration. Frozen anaerobic venous plasma samples were analyzed for pH, P(CO2), HCO3, Na(+), K(+), and Cl(-). Results similar to those found in submarine exposure showed the existence of a mild respiratory acidosis during days 1-24 of exposure and a compensation of the acidosis during days 25-45 of exposure. A second period of a mild respiratory acidosis developed during the latter days of exposure (46-90 days). All values rapidly returned to normal subsequent to exposure. (Author)