Effects of Trans alpha-Hydroxyl Groups in Alkaline Degradation of Glycosidic Bonds

摘要

The influence of alpha, beta-dihydroxyl groups in the alkaline hydrolysis of glucosidic bonds is examined. In derivatives of beta-D-glucopyranosides, all hydroxyl groups are trans to each other, and the alkaline elimination of substituted methyl ethers in positions C-2 and C-4 can be explained, in part, by assistance from neighboring trans alpha-hydroxyls. (Author)