Response Patterns of Amphibian Olfactory Bulb Neurones to Odour Stimulation.

摘要

Responses of 199 single olfactory bulb neurones were observed with odor stimulation. Some odor applications did not cause any change in the spontaneous activity of the unit, some applications caused an excitation during the rising concentration phase of the stimulus pulse, with three temporal patterns of excitatory responses that were categorized as subgroups, and some applications caused a suppression of ongoing activity. Each response type was seen with about the same frequency regardless of the odor used, suggesting that the temporal patterns of response per se were not coding for odor types. When odor concentration was manipulated for a unit showing suppressive activity at one concentration, then the unit tended to show qualitatively similar suppression at other concentrations as long as they were above threshold. When peak concentrations were manipulated for showing excitatory activity the temporal patterns of response could change dramatically. In many cases the units fired after one level of concentration had been reached and were subsequently suppressed with increase in concentration suggesting odor coding. (Author)