Experimental Human 'Trichophyton mentagrophytes' Infections.

摘要

Inflammatory dermatophytosis was induced on the ankles, thighs, or forearms of 40 men using purified spore suspensions of a granular strain of Trichophyton mentagrophytes. Standard reproducible infections resulted from the application of a quantitated dose of spores to a measured skin area, followed by continuous occlusion with a plastic patch for 4 days. Alternate methods of inducing infections included the use of infected skin scales as a source of spores and the substitution of damp clothing for the occlusive patch. The infection healed spontaneously in 90 days. There was no spread. (Author)