THE EFFECT OF LOCAL SUPRALETHAL IRRADIATION ON RENAL FUNCTION

摘要

Clearance studies were performed in 16 dogs with surgically formed hemi bladders to evaluate the intrinsic renal effects of 2000 rads of x rays administered as a single dose to the left kidney. These studies were conducted under conditions of water diuresis in 10 dogs on days 1, 7 and 14 post exposure. Additional studies were per-formed 21 and 28 days after exposure in eight of these dogs and 56 days later in four. Six dogs were studied under conditions of osmotic diuresis at all of these intervals.