Attention, Learning, and Personality During Ketamine Emergence: A Pilot Study.

摘要

Attention, learning, and personality changes were examined in a repeated measure design for 11 anesthesiologists after emergence from the initial effects of a 0.4 mgn/kg dose of ketamine (IV), an approved anesthetic. The results showed that attention is greatly reduced during induction but returns quickly to normal during emergence. New and illogical association were also difficult to process, but old and logical association were essentially intact. The personality changes were striking. Ketamine reduced normal environmental responsiveness and produced more bizarre personality responses. The implication for operating room and recovery procedures as well as the personality dynamic quality of the use of ketamine was discussed. (Author)