Neurogenic Influence on Pulmonary Surface Tension and Cholesterol in Cats (38609).

摘要

Previous clinical studies have shown that the sympathetic nervous system plays a major role in the development of acute pulmonary injury which is associated with mechanical head injury, surgical trauma and severe nonspecific stress. Similar findings in animals exposed to experimental head injury, hyperbaric oxygen, and sympathetic nerve stimulation suggest that, in addition to possible hemodynamic changes, sympathetic stimulation may alter the alveolar surfactants prior to the subsequent development of pulmonary congestion and edema. Previous work has shown that stimulation of the pulmonary sympathetics did not increase lung weight but decreased compliance and increased the minimum surface tension of the lung wash fluid as measured at maximal film compression on a surface tension balance.