Synthesis of Perfluoro-1,4-Dioxane, Perfluoro(ethyl Acetate), and Perfluoropivaloyl Fluoride by Direct Fluorination.

摘要

Recent advances in direct fluorination will make possible the synthesis of many important new oxygen-containing functional fluorocarbon molecules and provide a valuable synthetic route to complement existing synthetic methods. To demonstrate this potential for handling three separate functional groups the first successful fluorination of 1,4-dioxane, of pivaloyl fluoride, (CH3)3CCFO, and of a hydrocarbon ester to produce the corresponding perfluorocarbon analogs in good yields is reported. (Author)