Sustained Protection against Superficial Bacterial and Fungal Infection by Topical Treatment.

摘要

This report summarizes investigations (1) delineating simple reproducible bioassays for measuring bacteriostatic and bacteriocidal activity of topical antimicrobial agents; (2) delineating pitfalls in using the paired- comparison type of analysis for topical antibacterials; (3) quantifying the bacteriology of two common dermatoses, atopic dermatitis and psoriasis, and the effect of antibiotic therapies in these disorders; (4) delineating experimental models for the evaluation of steroid-antibiotic combinations; (5) describing a technique for experimental Candida albicans infections and its usefulness in evaluating anti-candida therapies; (6) describing the microbiology of the various species of interdigital eruptions of the feet and studies on various therapies for this condition; and (7) delineating in vitro and in vivo tests for the antimicrobial efficacy and stringent effects of various aluminum salts. (Author).