Diffusion Constant Measurements of Macromolecules in Solutions Containing Particulate Components.

摘要

The analysis and measurement of the dynamic properties of a monodispersed macromolecule in a solution containing a distribution of particulate contaminants are reported. The resulting measured diffusion constants have values that agree with the accepted values found by ultracentrifuge methods. The inclusion in the analysis of a simple approximation of the effects of the contaminant background eliminates the necessity of ultrapure samples, which are often impractical or impossible to prepare. (Author)