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Evaluating New Antimalarial Drugs against Trophozoite Induced 'Plasmodium cynomolgi' Malaria in Rhesus Monkeys.

机译：评估针对滋养体诱导的恒河猴疟疾疟疾的新型抗疟药物。

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摘要

An antimalarial drug testing system is described which utilizes trophozoite induced Plasmodium cynomolgi malaria in rhesus monkeys. The schizonticidal activity of standard antimalarial drugs in this system is reported. The system accurately predicted antimalarial activity in man of 8 of 9 compounds selected for clinical trials. (Author)

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作者
Davidson, D. E.; Johnsen, D. O.; Tanticharoenyos, P.; Hickman, R. L.; Kinnamon, K. E.;
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年度 1975
页码 1-10
总页数 10
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Antimalarials; Malaria; Chemotherapy; Rhesus monkeys; Test methods; Humans; Predictions; Drugs; Effectiveness; Physiological effects; Tolerances(Physiology); Reprints; Plasmodium cynomolgi; Schizonts;

机译：抗疟药;疟疾;化学疗法;恒河猴;试验方法;人类;预测;药物;有效性;生理影响;耐受性（生理学）;重印;食蟹猴; schizonts;

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1. 新型N-(2-芳基氨基苯基)-2,3-二苯基喹喔啉-6-磺胺类药物作为潜在抗疟疾、抗真菌和抗细菌药物的合理药物设计、合成和生物学评价 [J] . Ahmed Hassen Shntaif, Sharuk Khan, Ganesh Tapadiya, 数字中医药（英文） . 2021,第004期
2. Statistical model to evaluate in vivo activities of antimalarial drugs in a Plasmodium cynomolgi-macaque model for Plasmodium vivax malaria. [J] . Kocken CH, Remarque EJ, Dubbeld MA Antimicrobial agents and chemotherapy. . 2009,第2期

机译：统计模型，用于评估间日疟原虫疟疾的食蟹猴-猕猴模型中抗疟药物的体内活性。
3. Poly ICLC inhibits Plasmodium cynomolgi B malaria infection in rhesus monkeys. [J] . Puri SK, Dutta GP, Levy HB, Journal of interferon and cytokine research: The official journal of the International Society for Interferon and Cytokine Research . 1996,第1期

机译：Poly ICLC抑制猕猴的食蟹猴疟原虫B疟疾感染。
4. Poly ICLC inhibits Plasmodium cynomolgi B malaria infection in rhesus monkeys. [J] . Puri SK, Dutta GP, Levy HB, Journal of interferon and cytokine research: The official journal of the International Society for Interferon and Cytokine Research . 1996,第1期

机译：Poly ICLC抑制猕猴的食蟹猴疟原虫B疟疾感染。
5. Computational Evaluation of EGFR Dynamic Characteristics in Mutation-Induced Drug Resistance Prediction [C] . Baobin Duan, Bin Zou, Debby D. Wang, IEEE International Conference on Systems, Man, and Cybernetics . 2015

机译：突变诱导的耐药性预测中EGFR动态特征的计算评估
6. Antimalarial Drug Development: Characterization and Targeting of the Malaria Parasite Purine Uptake Pathway to Develop Novel Antimalarial Drugs [D] . Sosa, Yvett Darcie. 2020

机译：抗疟药作用：疟疾寄生虫嘌呤摄取途径的表征和靶向培养新型抗疟药
7. Statistical Model To Evaluate In Vivo Activities of Antimalarial Drugs in a Plasmodium cynomolgi-Macaque Model for Plasmodium vivax Malaria [O] . Clemens H. M. Kocken, Edmond J. Remarque, Martin A. Dubbeld, 2009

机译：评价疟原虫间日疟原虫食蟹猕猴模型中抗疟药物体内活性的统计模型。
8. Statistical model to evaluate in vivo activities of antimalarial drugs in a Plasmodium cynomolgi-macaque model for Plasmodium vivax malaria. [O] . Kocken, Clemens H M, Remarque, Edmond J, Dubbeld, Martin A, 2009

机译：统计模型，用于评估间日疟原虫疟疾的食蟹猴-猕猴模型中抗疟药物的体内活性。
9. 'Plasmodium cynomolgi'. Effects of Malaria Infection on Laboratory Flight Performance of 'Anopheles stephensi' Mosquitoes. [R] . Schiefer, B. A., Ward, R. A., Eldridge, B. F. 1976

机译：'疟原虫cynomolgi'。疟疾感染对'斯氏按蚊'实验室飞行表现的影响。

Evaluating New Antimalarial Drugs against Trophozoite Induced 'Plasmodium cynomolgi' Malaria in Rhesus Monkeys.

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