Morphine Dependency and Withdrawal: A Novel Finding for Dependency Control in Rats.

摘要

An isolated product from the condensation reaction of pyridoxal and dopamine reduces the wet dog shake episodes in morphine-dependent rats during nalozone-induced withdrawal. Treatment of morphine-dependent rats with either a large excess of B6 alone or pyridoxal alone and in combination with B6 also reduce the shake episode phenomenon. (Author)