Chemical Index to Fitness (Biochemical Correlates of Stress in Specialized Populations).

摘要

During the 6th and final year of this contract we published a report on our third neuroendocrine study of sleep, which examined the secretion patterns of the posterior pituitary hormone, antidiuretic hormone, in normal young adult men. This is the first reported study of the longitudinal secretion patterns of a posterior pituitary hormone in human subjects, and it was found that antidiuretic hormone was secreted episodically, like the anterior pituitary hormones, but with no change in integrated plasma levels throughout the night or any relation of the specific secretory episodes to any stages of sleep. Other aspects of this past year's work included the preparation of several invited chapters for textbooks of psychopharmacology and psychiatry. These studies are part of a continuing program of research into the biochemical and psychoendocrine correlates of stress, sleep and dreaming, and other central nervous system states in specialized populations as well as in normal subjects.