Protective Activity in Sera from Mice Immunized against 'Plasmodium berghei'.

摘要

Outbred WR ICR Br, Walter Reed, mice were immunized with repeated injections of irradiated Plasmodium berghei infected mouse erythrocytes. These donor mice were killed for sera 7 days after last immunization. Recipient mice were given daily injections of donor serum both before and after challenge with the nonirradiated parasite. There was evidence of serum related protective activity as shown by parasitemia data and mortality among the recipient mice. (Author)