Neurohumoral Control Mechanisms in the Regulation of Cardiovascular Function and Fluid and Electrolyte Balance.

摘要

Changes in cardiac output and peripheral resistance, and changes in the venous tone following bleeding and transfusion, and their correlation with the cardiac and sino-aortic receptor drive were studied. Additional studies were made of cardio-acceleratory sympathetic afferent pathways, physiology of Arterio-Venous(A-V) shunts, including the mechanism underlying cardiovascular adjustment in A-V shunts, and cardiovascular receptors discharge in A-V shunts. Also studied were the response of vagal afferents in shock and fainting, vagal and/or non-vagal pathways concerned with sympathetic outflow to the spleen and kidneys, and mechanisms of natriuresis produced by instillation of sodium into the third ventricle.