Attempted Synthesis of Pyridine Containing Bis-Alpha-Diketones via the Benzoin Condensation.

摘要

Although polyphenylquinoxalines are exceptional high-temperature-resistant resins, they are prohibitively expensive due largely to the high cost of the Bis-alpha-diketones from which they are prepared. The benzoin condensation of each of the three isomeric pyridine monocarboxaldehydes with terephthaldehyde followed by oxidation has been investigated as an alternate route to these monomers. Although all such attempts were unsuccessful, an insight into the complexities of mixed benzoin condensations is presented.