Study of a Possible Relationship between Bilharziasis and Nephrotic Syndrome in Upper Egypt.

摘要

Results obtained during last year study strongly solidify the hypothesis of a cause and effect relationship between schistosomiasis and Mesangiocapillary Glomerulonephritis. Expansion of the epidemiological study is needed for villages with various dates of irrigation in order to obtain a curve of a possible time. Prospective study of E.M. during the last 1.5 years was one of clear evidence for the development of heavy proteinuria following schistosomiasis. Further longitudinal study is required for that village. A yearly survey is planned. P.V.P. clearance test is of possible help in the prediction of individuals more prone to develop immunological diseases. The 69 individuals in whom P.V.P. clearance was determined are to be followed and examined every 6 months. An attempt is to be made to assess whether patients developing Glomerulonephritis with the exposure to a certain Ag (Schistosomiasis) are deficient in disposing immunocomplexes. Clinico immunological studies confirmed the high suspicious of the existence of a Schistosoma Associated Glomerulonephritis.