Biological Effects of Laser Radiation. Volume I. Review of the Literature on Biological Effects of Laser Radiation-to 1965

摘要

Research on biological effects of laser radiation to 1965 is reviewed. Laser production of free radicals, use in microscopy and holography, and tissue and cell culture effects are discussed. Possible beneficial transformations in macromolecular preparations are detailed. Effects on normal animals together with gross and microscopic studies are described. Benefits and hazards of applicability and relationship to animal tumor models are presented. Ophthalmological uses and hazards are covered. Protective systems, limitations in applicability of systems current at that time to ophthalmology and in experiments, are indicated. Possible use in dentistry and in entomology are reviewed. Mechanisms include consideration of thermal and non-thermal models, pigmentation, interfaces, steam production, pulse duration, non-linear and sonic waves, bubble production and collapse, charged particle production, hypersonic waves, and radiation scattering. Problems associated with measurement of temperature and pressure and methods for carrying out such measurements are presented. A section on non-linear effects discusses second harmonic generation in laser systems and production in target sites, Raman scattering and possible production of ultraviolet radiation. Effects and hazards are considered. Sections on gas lasers, flash lamps, electrical hazards and scattering are included. (Author)