Respiratory Adaptations in Acid-base Disturbances: Role of Cerebral Fluids.

摘要

The respiratory and metabolic components of acid-base homeostasis are defined. A quantitative empirical description of the (incomplete) mutual compensations in steady acid-base disturbances primarily occurring in either of the two components is presented, based upon data compiled from the literature. Respiratory adaptations in steady acid-base disturbances of metabolic origin (hyperventilation with hypocapnia in primary metabolic acidosis, and hypoventilation with hypercapnia in metabolic alkalosis) are analyzed as a function of the acidity of the cerebral fluids (cerebrospinal and cerebral interstitial fluid). (Author)