Targeted Radiation Therapy for Cancer Initiative.

摘要

This program is intended to establish the infrastructure to provide state-of-the art targeted radiation therapy to military personnel and veterans with cancer. The research aspect of this project is intended to demonstrate whether (1) targeted radiation therapy with real time localization and tracking will allow use of a smaller planning treatment volume margin with a significant decrease in rectal and bladder volume treated and whether the use of such targeted therapy can occur within standard treatment times and thus feasible for routine clinical use, (2) whether the use of Vac-Lok. immobilization devices are necessary when patients are treated using the Calypso system, (3) whether Beacon. Transponder is of benefit in pelvic radiation therapy following prostatectomy, (4) whether hypofractionated treatment plans which are more beam on time per fraction which may potentially account for more intra-fraction organ movement but allow for a shorter duration of treatment are feasible for routine clinical use with the Calypso system and (5) whether use of the Calypso system, and other advanced radiation therapy equipment, can improve treatment techniques and outcomes in malignancies arising in other parts of the body.