Topical Hazard Evaluation Program of Candidate Insect Repellents AI3-37221 and AI3-37225, 1-(3-cyclohexen-1-ylcarbonyl)-3-methylpiperidine and 1-(3-cyclohexen-1-ylcarbonyl)-4-methylipiperazine

摘要

Preliminary hazard evaluations of AI3-37221 and AI3-37225 were performed by means of laboratory animal studies using rabbits and guinea pigs. Both technical grade compounds caused moderate corneal and conjunctival irritations. AI3-37221 caused mild primary skin irritation; AI3-37225 caused no such reaction. AI3-37225 was tested for skin sensitization and found to be negative. (Author)