Primary Ocular Irritation of Two CHF 1 Formulation Components: Dow Corning 200 and Isopropanol

摘要

The primary ocular irritation potential of two formulation components of CHF 1, Dow Corning 200 fluid and isopropanol, was tested using the methods outlined by Draize and Kelly. A 25% solution of each was used to duplicate their concentration of CHF 1. Both were negative for ocular irritation at the concentration used. Twenty-five percent Dow Corning 200 fluid was slightly more irritating than isopropanol at the same concentration. (Author)