Effects of Heat Acclimation on Atropine Impaired Thermoregulation

摘要

The effects of saline or atropine injection (2 mg, im) on eccrine sweating and performance time in seven healthy male subjects were evaluated during treadmill walking in a hot-dry environment, before and after heat acclimation. Mean skin temperature, rectal temperature, and heart rate were continuously measured. Data demonstrated that heat acclimation improves the endurance time of atropine-treated subjects in a hot-dry environment. This improvement was in part due to the potentiation of sweat gland activity enabling greater evaporative cooling for the same dose of atropine.