Acute Intramuscular Toxicity (LD50) of 1,1'-Methylenebis (4-(Hydroxyimino) Methyl) Pyridinium Dibromide, (MMB-4) in Male Mice

摘要

The acute intramuscular toxicity of MMB-4 was determined in male ICR mice by using the single dose method. LD(1), LD(50), and LD(95) with their 95% confidence limits were calculated by probit analysis. The LD(50) was 448 mg/kg with the 95% confidence limit (398 mg/kg, 506 mg/kg). The MMB-4 formulation falls in the very toxic range.