Changes in Rhesus Contrast Sensitivity Associated with Laser Induced Punctate Foveal Lesions

摘要

The effects of small, punctate foveal laser exposures on rhesus spatial contrast sensitivity were investigated. The immediate effects of such exposure revealed generalized depression in sensitivity that was transient and nearly uniform across the measured spatial frequency spectrum. Funduscopic observation revealed punctate lesioned areas in the foveal-macular region of all animals following exposure. While long-term effects on high spatial frequency contrast sensitivity were virtually nonexistent, changes in the slope of the spatial contrast sensitivity function suggested the presence of residual alteration of foveal spatial vision.