Generalized Rank Annihilation Factor Analysis

摘要

The method of rank annihilation is shown to be a particular case of a more general method for quantitation in bilinear data arrays such as LC/UV, GC/MS or emission-excitation fluorescence. Generalized rank annihilation is introduced as a calibration method that allows for simultaneous quantitative determination of all the analytes of interest in a mixture of unknowns. Only one calibration mixture is required. The bilinear spectra of both unknown and calibration sample must be obtained. Bilinear target factor analysis is introduced as a projection of a target bilinear matrix onto another principal component bilinear matrix space.