9-O-(1,2:5,6-Di-O-Isoprepylidene-Alpha-D-Glucofuranosyl)-9- Boratabicyclo(3.3.1)Nonane. A New, Effective Chiral Borohydride Reagent

摘要

A convenient and simple synthesis of a new chiral borohydride reagent, potassium 9-0-(1,2:5,6-di-0-isopropylidene-alpha-D-glucofuranosyl)-9- boratabicyclo-3.3.1 nonane, consisting of a single reducing species, is described. The new reagent is generally effective for the asymmetric reduction of aklyl phenyl ketones and hindered aliphatic ketones. (Author)