Bloody Diarrhoea after Praziquantel Therapy.

摘要

Four out of 20 patients with Schistosoma japonicum infection who received praziquantel developed a syndrome of severe abdominal pain followed by bloody diarrhea. Symptoms occurred shortly after completion of the 60 mg per kg course of treatment and were self-limited. The co-existence of occult blood in pre-treatment stool specimens and severe liver disease were risk factors for developing post-praziquantel bloody diarrhea but its pathophysiology is not currently known.