Design Automation Software for DNA-Based Nano-Sensor Architecture.

摘要

This project was developed in response to an RFA seeking innovations to create DNA molecules that self-assemble to support nanomolecular design. While the solicitation emphasized software to solve the challenges arising from the intrinsic chemistry of DNA, which is built from just four nucleotides (GACT), the premise of this project was that the design task could be rendered trivial if standard DNA were augmented extra nucleotides to give an 'artificially expanded genetic information system' (AEGIS).