Chromatographic and Mass Spectrometric Separation and Analysis

摘要

A final scientific report is given for research in the areas of chromatographic separations and mass spectrometry. A new porous polymer containing cobalt has been synthesized and characterized. It has been found to bind molecular oxygen reversibly. Additional characterization has been made of a symmetrical multidendate ligand, when chelated with a suitable metal ion, potentially may be a new shift reagent for nuclear magnetic resonance spectrometry. Tandem mass spectrometry has been investigated as a new means of characterize various metal chelates. Significant differences have been observed for fragment ions produced by collisionally activated dissociation compared to electron impact ionization. Chromium chelates of a beta-diketone have shown exceptional stability in chromatographic systems, yielding new procedures for separating various chromium species. Experiments with a supercritical fluid chromatograph have indicated the potential to use the device with selective chromatographic detectors and for separations that are difficult to effect by gas chromatography. Keywords: Selective sorbents, chromatographic phases, metal chelates NMR shift reagents, mass spectrometry, tandem mass spectrometry, supercritical fluid chromatography.