Correlative Motor Behavioral and Striatal Dopaminergic Alterations Induced by 56Fe Radiation.

摘要

In the present study, it became of interest to determine if there could be a radiation-induced of autoreceptor function that could be related to the deficits in motor behavior that have been observed in irradiated animals. The present experiment was directed toward making these observations by examining motor behavioral performance in rats exposed to HZE's and relating the degree of alteration of such performance to any observed deficits in muscarinic enhancement of the K(+)-evoked release of DA from superfused striatal slices. Keywords: HZE (Heavy Charged Particles), Iron, Radioactive isotopes, Dopamine, Radiation effects, Reprints. (AW)